abstract：:Acetaminophen-induced hepatotoxicity is a common consequence of acetaminophen overdose and may lead to acute liver failure (ALF). Currently acetaminophen is the most common cause of ALF in both United States and United Kingdom, with a trend to increasing incidence in the United States. N-acetylcysteine is the most eff...

journal_title：Journal of clinical gastroenterology

authors： Chun LJ,Tong MJ,Busuttil RW,Hiatt JR

更新日期：2009-04-01 00:00:00

abstract：BACKGROUND:The implications of the Rome III recommendations to change the irritable bowel syndrome (IBS) subtype criteria for stool pattern are unknown. AIM:(1) Determine the level of agreement between Rome II and Rome III subtypes and (2) compare the behaviors of Rome II and Rome III subtypes over time. METHODS:Fema...

journal_title：Journal of clinical gastroenterology

authors： Dorn SD,Morris CB,Hu Y,Toner BB,Diamant N,Whitehead WE,Bangdiwala SI,Drossman DA

更新日期：2009-03-01 00:00:00

abstract：BACKGROUND:The presence of laryngopharyngeal reflux disease is controversial when abnormal sensation of the laryngopharynx is felt without heartburn. GOALS:The aims of this study were to investigate the relationship between abnormal sensation of the laryngopharynx and gastroesophageal reflux, and to elucidate the path...

journal_title：Journal of clinical gastroenterology

authors： Wada T,Sasaki M,Kataoka H,Ogasawara N,Kanematsu T,Tanida S,Nojiri S,Ando T,Okochi M,Joh T

更新日期：2009-03-01 00:00:00

abstract：BACKGROUND:The sensitivity and specificity of current antihuman tissue transglutaminase (tTG) IgA assays used to detect celiac disease reportedly approach 100%. In addition, the sensitivity of new generation deamidated gliadin peptide (alpha-DGP) antibody assays has also been reported to be similar to the tTG IgA assay...

journal_title：Journal of clinical gastroenterology

authors： Naiyer AJ,Hernandez L,Ciaccio EJ,Papadakis K,Manavalan JS,Bhagat G,Green PH

更新日期：2009-03-01 00:00:00

abstract：BACKGROUND AND GOALS:Chronic inflammation associated with Helicobacter pylori infection is a risk factor of gastric adenocarcinoma. Interleukin-8 (IL-8) plays an important role in gastric mucosal inflammation induced by H. pylori infection. Recently, studies on the association of genetic polymorphisms of various proinf...

journal_title：Journal of clinical gastroenterology

authors： Ye BD,Kim SG,Park JH,Kim JS,Jung HC,Song IS

更新日期：2009-03-01 00:00:00

abstract：:Copper deficiency is an uncommonly reported complication of celiac disease that has not received much attention in recent years. Copper deficiency may result in anemia and thrombocytopenia and also irreversible myeloneuropathy if it is not detected and treated appropriately. The prevalence of copper deficiency in pati...

journal_title：Journal of clinical gastroenterology

authors： Halfdanarson TR,Kumar N,Hogan WJ,Murray JA

更新日期：2009-02-01 00:00:00

abstract：BACKGROUND:The rate of Helicobacter pylori is decreasing in the developed countries, but few long-term studies are available from the United States. We retrospectively assessed the annual H. pylori infection rate in symptomatic children seen in our clinic over a 13-year study period. STUDY:A retrospective analysis of ...

journal_title：Journal of clinical gastroenterology

authors： Elitsur Y,Dementieva Y,Rewalt M,Lawrence Z

更新日期：2009-02-01 00:00:00

abstract：BACKGROUND:The aims of this study were to analyze the overall survival of patients with cirrhosis and small hepatocellular carcinoma (HCC) and identify independent pretreatment predictors of survival in Brazil. METHODS:Between 1998 and 2003, 74 patients with cirrhosis and small HCC were evaluated. Predictors of surviv...

journal_title：Journal of clinical gastroenterology

authors： Kikuchi LO,Paranaguá-Vezozzo DC,Chagas AL,Mello ES,Alves VA,Farias AQ,Pietrobon R,Carrilho FJ

更新日期：2009-02-01 00:00:00

abstract：BACKGROUND:Guidelines recommend upper endoscopic screening of cirrhotic patients for gastroesophageal varices. Cirrhosis is not always distinguishable from chronic hepatitis. GOALS:To identify low-risk patients who can be spared upper endoscopy irrespective of a diagnosis of cirrhosis. STUDY:We evaluated 13 nonendosc...

journal_title：Journal of clinical gastroenterology

authors： Gentile I,Viola C,Graf M,Liuzzi R,Quarto M,Cerini R,Piazza M,Borgia G

更新日期：2009-01-01 00:00:00

abstract：:The term "diverticulitis" indicates the inflammation of a diverticulum or diverticula, which is accompanied by detectable or microscopical perforation. Diverticulitis is a common condition with an estimated incidence of 25%. At present, elective sigmoid resection is recommended after 2 episodes of uncomplicated divert...

journal_title：Journal of clinical gastroenterology

authors： Comparato G,Di Mario F,NDSG.

更新日期：2008-11-01 00:00:00

abstract：GOALS:Follicular lymphoma (FL) is a common nodal lymphoma. Primary gastrointestinal follicular lymphoma (GIFL) is rare and most commonly occurs in the elder women with indolent clinical course, mainly in the duodenum and terminal ileum. We conducted this study to characterize GIFL in Taiwan. STUDY:A total of 13 cases ...

journal_title：Journal of clinical gastroenterology

authors： Huang WT,Hsu YH,Yang SF,Chuang SS

更新日期：2008-10-01 00:00:00

abstract：GOALS:The current study presents 1 tertiary endoscopy center's 20-year experience using endoscopic therapy to treat patients with symptomatic primary sclerosing cholangitis (PSC). BACKGROUND:Endoscopic therapy for patients with PSC and dominant strictures has been used for more than 20 years, but there is concern that...

journal_title：Journal of clinical gastroenterology

authors： Gluck M,Cantone NR,Brandabur JJ,Patterson DJ,Bredfeldt JE,Kozarek RA

更新日期：2008-10-01 00:00:00

abstract：OBJECTIVE:Abnormal pancreatic function tests have been reported to precede the imaging findings of chronic pancreatitis. Magnetic resonance imaging (MRI) with magnetic resonance cholangiopancreatography (MRCP) is increasingly accepted as the primary imaging modality for the detection of structural changes of early mild...

journal_title：Journal of clinical gastroenterology

authors： Alkaade S,Cem Balci N,Momtahen AJ,Burton F

更新日期：2008-09-01 00:00:00

abstract：:Food sensitivities are constantly increasing in "westernized" countries and may pose serious health risks to sensitized individuals. Severe allergy episodes have also been reported after the intake of probiotic products containing milk protein residues, especially in children. The need for safe and effective probiotic...

journal_title：Journal of clinical gastroenterology

authors： Mogna G,Strozzi GP,Mogna L

更新日期：2008-09-01 00:00:00

abstract：AIM:To define whether human colonic mucosa exposure to Lactobacillus rhamnosus GG (LGG), American Type Culture Collection (ATCC) 53103, may influence intestinal muscle cell contractility. METHODS:Human colon specimens were obtained from disease-free margins of resected segments for cancer. The mucosa and submucosa, af...

journal_title：Journal of clinical gastroenterology

authors： Guarino MP,Altomare A,Stasi E,Marignani M,Severi C,Alloni R,Dicuonzo G,Morelli L,Coppola R,Cicala M

更新日期：2008-09-01 00:00:00

abstract：GOALS:The goal of this study was to examine the effect of a standardized silybin and soy phosphatidylcholine complex (IdB 1016) on serum markers of iron status. BACKGROUND:Milk thistle and its components are widely used as an alternative therapy for liver disease because of purported antioxidant, anti-inflammatory, an...

journal_title：Journal of clinical gastroenterology

authors： Bares JM,Berger J,Nelson JE,Messner DJ,Schildt S,Standish LJ,Kowdley KV

更新日期：2008-09-01 00:00:00

abstract：:Severe sepsis with associated multisystem organ dysfunction is a leading cause of death in patients hospitalized in intensive care units. The gastrointestinal system plays a key role in the pathogenesis of multisystem organ dysfunction owing to a breakdown of intestinal barrier function and increased translocation of ...

journal_title：Journal of clinical gastroenterology

authors： Madsen K

更新日期：2008-09-01 00:00:00

abstract：PURPOSE:The purpose of this study is to compare the sensitivity of computed tomography (CT) colonography (CTC) with that of colonoscopy for detecting patients with colorectal polyps in an asymptomatic screening population in Korea, thus to evaluate a possibility, whether CTC could be used as a screening tool for colore...

journal_title：Journal of clinical gastroenterology

authors： Kim YS,Kim N,Kim SH,Park MJ,Lim SH,Yim JY,Cho KR,Kim SS,Kim DH,Eun HW,Cho KS,Kim JH,Choi BI,Jung HC,Song IS,Shin CS,Cho SH,Oh BH

更新日期：2008-08-01 00:00:00

abstract：:Extrahepatic biliary atresia (EHBA), an inflammatory sclerosing cholangiopathy, is the leading indication for liver transplantation in children. The cause is still unknown, although possible infectious, genetic, and immunologic etiologies have received much recent focus. These theories are often dependent on each othe...

journal_title：Journal of clinical gastroenterology

authors： Bassett MD,Murray KF

更新日期：2008-07-01 00:00:00

abstract：BACKGROUND:Diagnosis of gastroesophageal reflux disease (GERD) based on subjective evaluation of symptoms alone is challenging. GOALS:To test the validity and reliability of a graded response questionnaire to identify patients with GERD. STUDY:Patients presenting with upper abdominal symptoms for more than a month, a...

journal_title：Journal of clinical gastroenterology

authors： Ho KY,Gwee KA,Khor JL,Selamat DS,Yeoh KG

更新日期：2008-07-01 00:00:00

abstract：BACKGROUND:Endoscopic follow-up (FU) in patients treated for colorectal adenomas or cancer (CRC) is intended to reduce the incidence of CRC. In the Dutch postpolypectomy guidelines, the FU interval is solely determined by the number of previous adenomas, whereas in other countries size and histology are also taken into...

journal_title：Journal of clinical gastroenterology

authors： Mulder SA,Ouwendijk RJ,van Leerdam ME,Nagengast FM,Kuipers EJ

更新日期：2008-05-01 00:00:00

abstract：:Esophageal manometry is a specialized procedure used to evaluate lower and upper esophageal sphincter pressure, esophageal body contraction amplitude, and peristaltic sequence. The procedure is clinically useful in evaluation of a patient with nonstructural dysphagia, unexplained or noncardiac chest pain, a compendium...

journal_title：Journal of clinical gastroenterology

authors： Katz PO,Menin RA,Gideon RM

更新日期：2008-05-01 00:00:00

abstract：:The single technological advancement that Bravo pH monitoring offers over conventional pH monitoring is the elimination of the transnasal catheter. This was not a trivial advance in terms of technologic achievement. Development of a delivery system that could temporarily place a wireless capsule on the esophageal muco...

journal_title：Journal of clinical gastroenterology

authors： Pandolfino JE,Kwiatek MA

更新日期：2008-05-01 00:00:00

abstract：BACKGROUND:Self-expanding metal stents (SEMSs) are used to treat malignant stenosis of the gastrointestinal (GI) tract, as a safe, feasible, and minimally invasive option for reestablishing luminal patency. However, the literature offers scant prospective data on the clinical outcome of these patients. AIM:To assess t...

journal_title：Journal of clinical gastroenterology

authors： Masci E,Viale E,Mangiavillano B,Contin G,Lomazzi A,Buffoli F,Gatti M,Repaci G,Teruzzi V,Fasoli R,Ravelli P,Testoni PA

更新日期：2008-04-01 00:00:00

abstract：OBJECTIVE:To manage hepatocellular carcinoma (HCC) patients surviving for a long term, the treatment strategy for recurrent cancer is as important as that for the initial treatment. However, no prognostic scoring system has been available for patients with HCC recurrence. The purpose of this study was to develop a new ...

journal_title：Journal of clinical gastroenterology

authors： Toyama T,Hiramatsu N,Yakushijin T,Oze T,Nakanishi F,Yasumaru M,Mochizuki K,Kanto T,Takehara T,Kasahara A,Hayashi N

更新日期：2008-03-01 00:00:00

abstract：GOALS:Our objective was to determine whether high serologic IgA tissue transglutaminase antibodies (TTGA) are exclusively associated with celiac disease (CD). BACKGROUND:IgA TTGA are found in the serum of most individuals with CD. This serologic marker is used to screen individuals with suspected CD for duodenal biops...

journal_title：Journal of clinical gastroenterology

authors： Donaldson MR,Book LS,Leiferman KM,Zone JJ,Neuhausen SL

更新日期：2008-03-01 00:00:00

abstract：BACKGROUND:Data on Asian patients who present to primary care physicians with dyspepsia are limited. AIM:To determine predictors of response to a trial of proton pump inhibitor therapy. METHOD:One hundred ninety patients presenting to their general practitioners with dyspeptic symptoms but without alarm symptoms, und...

journal_title：Journal of clinical gastroenterology

authors： Gwee KA,Hwang JE,Ho KY,Yeoh KG,Lum CF,Ang PK

更新日期：2008-02-01 00:00:00

abstract：AIM/BACKGROUND:Achalasia may be associated with extraesophageal dysmotility. However, this relation is still poorly understood. In the present study, we used noninvasive real-time ultrasonography to examine the motility function of the gallbladder in the patients with achalasia. MATERIALS AND METHODS:Thirty-three acha...

journal_title：Journal of clinical gastroenterology

authors： Alagozlu H,Unal S,Karakan T,Cindoruk M,Ergun M

更新日期：2008-02-01 00:00:00

abstract：GOALS:To evaluate the diagnostic yield of push enteroscopy in relation to indication and compare the yield in patients who had capsule endoscopy followed by push enteroscopy against capsule endoscopy naive patients. BACKGROUND:With the advent of capsule endoscopy the role of push enteroscopy needs to be reevaluated. ...

journal_title：Journal of clinical gastroenterology

authors： Sidhu R,McAlindon ME,Kapur K,Hurlstone DP,Wheeldon MC,Sanders DS

更新日期：2008-01-01 00:00:00

abstract：:Gastroesophageal varices are a direct consequence of portal hypertension. Nonselective beta-adrenergic blockers decrease portal pressure and are effective in preventing variceal hemorrhage. However, a large multicenter placebo-controlled trial demonstrates that nonselective beta-adrenergic blockers are not effective i...

journal_title：Journal of clinical gastroenterology

authors： Garcia-Tsao G

更新日期：2007-11-01 00:00:00

abstract：BACKGROUND:Intrahepatic cholangiocarcinoma (ICC) is a highly fatal disease with limited therapeutic options. The determinants, trends, and outcomes of different therapies for ICC are largely unknown in the United States. METHODS:Using data from the Surveillance, Epidemiology, and End-Results-(SEER) Medicare database, ...

journal_title：Journal of clinical gastroenterology

authors： Shaib YH,Davila JA,Henderson L,McGlynn KA,El-Serag HB

更新日期：2007-11-01 00:00:00

abstract：BACKGROUND:Tormentil extracts (TE) have antioxidative properties and are used as a complementary therapy for chronic inflammatory bowel disease. In individual patients with ulcerative colitis (UC) positive effects have been observed. GOALS:To assess the safety, pharmacology, and clinical effects of different doses of ...

journal_title：Journal of clinical gastroenterology

authors： Huber R,Ditfurth AV,Amann F,Güthlin C,Rostock M,Trittler R,Kümmerer K,Merfort I

更新日期：2007-10-01 00:00:00

abstract：:Hyper-transaminasemia (HT) is a well-known laboratory sign of celiac disease (CD); however, hyper-creatine phosphokinase (CK)-emia (HCK) is not so familiar. As there are reported cases of myopathy associated CD in the literature, we aimed to investigate serum CK levels of children with CD. Newly diagnosed 126 children...

journal_title：Journal of clinical gastroenterology

authors： Selimoglu MA,Ertekin V,Altinkaynak S

更新日期：2007-08-01 00:00:00

abstract：:Helicobacter pylori has been implicated in the pathogenesis of a number of digestive tract disorders, such as chronic active gastritis, peptic ulceration, gastric cancer, and mucosa-associated lymphoid tissue lymphoma. Disease outcome is dependent on many factors, including bacterial genotype, host physiology and gene...

journal_title：Journal of clinical gastroenterology

authors： Makola D,Peura DA,Crowe SE

更新日期：2007-07-01 00:00:00

abstract：OBJECTIVES:Hepatic ultrasound (US) is readily available and physicians usually trust the results of an US report suggesting fatty liver, but there are conflicting reports on its accuracy, especially in patients with chronic liver disease (CLD). Therefore, we retrospectively examined liver biopsies in patients with CLD ...

journal_title：Journal of clinical gastroenterology

authors： Perez NE,Siddiqui FA,Mutchnick MG,Dhar R,Tobi M,Ullah N,Saksouk FA,Wheeler DE,Ehrinpreis MN

更新日期：2007-07-01 00:00:00

abstract：BACKGROUND AND GOALS:Neurohormonal factors might play a role in the pathogenesis of functional dyspepsia (FD). However, the role of ghrelin, a gastrointestinal hormone that stimulates gastric motility, in FD is not yet clearly defined. The present study was designed to investigate plasma ghrelin levels and their relati...

journal_title：Journal of clinical gastroenterology

authors： Takamori K,Mizuta Y,Takeshima F,Akazawa Y,Isomoto H,Ohnita K,Ohba K,Omagari K,Shikuwa S,Kohno S

更新日期：2007-05-01 00:00:00

abstract：:The practice of gastroenterology is undergoing sweeping changes that demand improvements in efficiency and effectiveness within the practice and ambulatory endoscopy centers. This article discusses core principles of practice and endoscopic ambulatory surgery center function and management that lead to the improvement...

journal_title：Journal of clinical gastroenterology

authors： Overholt BF

更新日期：2007-04-01 00:00:00

abstract：:Here we reported the first case in Taiwan of human intestinal myiasis caused by larvae of Telmatoscopus albipunctatus. The 21-year-old male patient experienced gastroenteritis and anal itching. During the patient's first hospital visit the doctor suspected Enterobius infection. After treatment with anthelmintic mebend...

journal_title：Journal of clinical gastroenterology

authors： Tu WC,Chen HC,Chen KM,Tang LC,Lai SC

更新日期：2007-04-01 00:00:00

abstract：:In the past there has been reliance on heartburn and acid regurgitation as the cardinal symptoms of gastro-esophageal reflux. Now it is recognized that diverse additional symptoms including extraesophageal manifestations are essential components of gastroesophageal reflux disease (GERD). Furthermore, previous reliance...

journal_title：Journal of clinical gastroenterology

authors： Modlin IM,Malfertheiner P,Hunt RH,Armstrong D,Holtmann G,Quigley EM,Spechler SJ

更新日期：2007-03-01 00:00:00

abstract：:Desmoid tumors may occur sporadically or as part of the extraintestinal manifestations of familial adenomatous polyposis. Different phenotypes have been described and some genotype-phenotype correlations have been raised, associated with different sites of germline mutations in the adenomatous polyposis coli (APC) gen...

journal_title：Journal of clinical gastroenterology

authors： Benoit L,Faivre L,Cheynel N,Ortega-Deballon P,Facy O,Marty M,Olschwang S,Fraisse J,Cuisenier J

更新日期：2007-03-01 00:00:00